KoiZymeKoizyme is a biological formula of naturally occurring bacteria, enzymes and micro nutrients. When Koizyme is introduced into pond water that is infected with Aeromonas, Pseudomonas or any gram negative or gram positive bacteria, the bacteria and enzymes in Koizyme competes with these pathogens for the nutrients in the pond water. These nutrients are primarily a nitrogen based nutrient from fish waste. Koizyme will consume these nutrients and starve Aeromonas and Psuedomonas. The bacteria counts (CFU’s) of these pathogens will then be reduced to such a low level that they will not have an affect on the fish. When used as directed, Koizyme will reduce the bacterial count of Aeromonas, Pseudomonas and other pathnogenetic bacteria to such low levels that they will not be a threat to the health of your fish. We recommend that you select 2 DAY AIR to ship this product during the hot summer months as it is affected by the heat. Shelf life 4 months at room temperature or 15 months w KoiZyme 16 oz KoiZyme